Table 2. APH Reductions of Ketonesa.
substrate | catalyst | t/h | conv % | ee % |
---|---|---|---|---|
13 | 4 | 16 | 100 | 94 (R) |
13 | 9 | 16 | 100 | 84 (R) |
14 | 4 | 16 | 70 | 84 (R) |
17 | 4 | 24 | 100 | 91 (S) |
17 | 9 | 24 | 94 | 88 (S) |
22 | 4 | 24 | 98 | >99 (R) |
22 | 9 | 24 | 100 | 99 (R) |
23 | 4 | 48 | 100 | 99 (R) |
23 | 9 | 48 | 60 | 99 (R) |
26 | 4 | 48 | 99 | 37 (S) |
26 | 9 | 48 | 40 | 81 (S) |
27 | 4 | 48 | 95 | 98 (R) |
27 | 9 | 48 | 72 | 95 (R) |
28 | 4 | 16 | 100 | 94 (R) |
28 | 9 | 16 | 100 | 80 (R) |
29 | 4 | 16 | 98 | 92 (R) |
29 | 9 | 16 | 99 | 74 (R) |
30 | 4 | 24 | 100 | 82 (R) |
31 | 4 | 48 | 32 | 80 (R) |
32 | 4 | 24 | 100 | 95 (S) |
Conv % and ee % calculated as for Table 1.