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. Author manuscript; available in PMC: 2013 Dec 9.
Published in final edited form as: Open Endocrinol J. 2010;4:10.2174/1874216501004010040. doi: 10.2174/1874216501004010040

Figure 11. Effects of exogenous insulin on the insulin signaling pathway.

Figure 11

Human (A) or rat islets (B) (100) were cultured for 4 days in CMRL as indicated and 3H-thymidine incorporation was determined during the final 24 h. Data are the means ± SE of n = 3 experiments with triplicate samples in each experiment. **p<0.01 and ***p<0.001 denote significant differences between the bracketed conditions. (C and D) Human islets (100) were treated for 30 min in CMRL as indicated and processed for Western Blotting. β-Actin was used as a protein loading control. Data are the means ± S.E. of n = 3 (C) or 2 (D) experiments. **p<0.01 indicates significant difference between the bracketed conditions. Reprinted with permission from ref. [57].