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. Author manuscript; available in PMC: 2013 Dec 9.
Published in final edited form as: Open Endocrinol J. 2010;4:10.2174/1874216501004010040. doi: 10.2174/1874216501004010040

Figure 2.

Figure 2

(A) Glucose enhances DNA synthesis in a rapamycin-sensitive manner. Rat islets (100) were cultured for 4 days in CMRL-1066 culture media (CMRL) as indicated. 3H-thymidine incorporation was determined during the final 24 h. Data are representative of two experiments with triplicate samples. Reprinted with permission from ref. [52]. (2B) Stimulatory effect of glyburide on DNA synthesis at basal glucose is modulated by Ca2+ influx. Rat islets (100) were cultured for 4 days in CMRL as indicated and 3H-thymidine incorporation determined during the final 24 h. Data are the means ± S.E. of n = 3 experiments with triplicate samples. Reprinted with permission from ref. [56].