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. Author manuscript; available in PMC: 2014 Dec 26.
Published in final edited form as: Neuroscience. 2013 Oct 10;255:10.1016/j.neuroscience.2013.09.057. doi: 10.1016/j.neuroscience.2013.09.057

Figure 5.

Figure 5

VTA dopamine depletion attenuates temporal expectation in a simple reaction time task with two-delays. While VTA dopamine depletion did not change accuracy (A), control animals developed delay-dependent speeding and (B), animals with VTA dopamine depletion did not. They did nvvot learn delay-dependent speeding with further training. (C) Levodopa administration in VTA dopamine-depleted animals restored delay-dependent speeding. * indicates significant differences via a t-test at p<0.05; + indicates a significant interaction between dopamine depletion and delay-length in a linear random-effects model.