FIG. 2.
Fibrous (B) and 45S5 Bioglass®-based (C) scaffolds seeded with hASC after investigation in the chorioallantoic membrane angiogenesis assay. Poor angiogenic responses could be detected with cell free scaffolds and with hernia meshes and 45S5 Bioglass®-based scaffolds seeded with human fibroblasts (HF) (A, D, E). Statistical analysis of the quantification of ingrown blood vessels proved a significant higher number of ingrown blood vessels with hASC seeded on hernia meshes compared to HF seeded on hernia meshes (*). hASC seeded on 45S5 Bioglass®-based scaffolds showed similar angiogenic effects (**): compared to HF seeded onto 45S5 Bioglass®-based scaffolds, hASC seeded onto 45S5 Bioglass®-based scaffolds showed significant higher number of ingrown blood vessels. Scale bars represent 1 mm. CAM, chorioallantoic membrane. Color images available online at www.liebertpub.com/tea
