Extracellular matrix organization of scaffolds with monocultures of human mesenchymal stem cells (hMSCs; M1, M2, O1, O2) and cocultures of hMSCs with human umbilical vein endothelial cells (HUVECs; MH, OH, and OMH) imaged via scanning electron microscopy (SEM). Magnification 100×, scale bar is 500 μm and applies for all images. Note the absence of the matrix and the lack of any mineralization on the scaffolds with endothelial cells (H) although cells are still present on the poly(ɛ-caprolactone) (PCL) fibers.