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. 2013 Nov;2(6):768–773. doi: 10.3978/j.issn.2225-319X.2013.10.07

Table 1. Summary of the reported results of conventional and minimally invasive approaches for repair of Barlow’s disease or bileaflet mitral prolapse.

Author Approach Number of patients (etiology) Follow-up Freedom from > moderate or ≥ moderate MR
David et al. [2005] (24) Sternotomy 250 (Bileaflet, incl. Barlow’s) 12 years 67%
Flameng et al. [2008] (25) Sternotomy 83 (Barlow’s) and 265 (FED) 5 years; 10 years 82.2%; 64.9%
Jouan et al. [2012] (26) Sternotomy 200 (Barlow’s) 8 years 90.2%
Castillo et al. [2013] (27) Sternotomy, lower hemi-sternotomy 110 (Barlow’s) and 78 (FED) 1 year; 4 years; 7 years 100%; 93.7%; 90.3%
Lapenna et al. [2005] (23) MIS 48 (Barlow’s) 22.7±10.6 months 99.9%
Speziale et al. [2011] (28) Sternotomy vs. MIS (Randomized) 70 (Barlow’s); 70 (Barlow’s) 12.4 months 97% (P=0.9); 98% (P=0.9)

MR, Mitral regurgitation; MIS, Minimally invasive surgery; FED, Fibroelastic deficiency.