Table 5. Perioperative clinical and time-related outcomes of patients who underwent mitral valve repair through a minimally invasive thoracotomy versus conventional sternotomy approach.
| Outcomes | Included studies | Overall statistics | ||||
|---|---|---|---|---|---|---|
| Clinical outcomes | No. of studies | MIMVR (n) | Sternotomy (n) | Relative risk (95% CI) | P-value | I2 (%) |
| Mortality | 7 | 952 | 1,011 | 1.23 (0.22-6.88) | 0.81 | 0 |
| Cerebrovascular accidents* | 6 | 906 | 929 | 1.43 (0.74-2.76) | 0.29 | 0 |
| Renal failure | 3 | 284 | 305 | 0.96 (0.31-3.00) | 0.95 | 0 |
| Wound infection | 4 | 634 | 670 | 2.97 (0.47-18.87) | 0.25 | 29 |
| Reoperation for bleeding | 6 | 848 | 896 | 1.25 (0.60-2.62) | 0.55 | 35 |
| Aortic dissection | 4 | 688 | 724 | 4.84 (0.55-42.43) | 0.15 | 0 |
| Myocardial infarction | 3 | 284 | 305 | 1.15 (0.24-5.64) | 0.86 | 0 |
| Readmission within 30 days | 2 | 308 | 315 | 0.61 (0.31-1.21) | 0.16 | 0 |
| Time-related outcomes | No. of studies | MIMVR (n) | Sternotomy (n) | Standard mean difference (95% CI) | P-value | I2 (%) |
| Cross-clamp time | 6 | 852 | 911 | 1.47 (0.52-2.42) | 0.003 | 99 |
| CPB time | 6 | 952 | 1,011 | 1.46 (0.40-2.51) | 0.007 | 99 |
| ICU stay | 2 | 247 | 247 | –0.77 (–1.36-0.17) | 0.01 | 88 |
| Length of hospitalization | 4 | 658 | 694 | –0.24 (–0.65-0.18) | 0.26 | 92 |
MIMVR, minimally invasive mitral valve repair; CI, confidence interval; *, includes stroke with or without transient ischaemic attack; CPB, cardiopulmonary bypass; ICU, intensive care unit.