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(a) Nitrite production and (b) cell viability of RAW macrophages treated with free and encapsulated resiquimod. Both graphs show results from one experiment run in triplicate (n = 3). Error bars represent one standard deviation. An * indicates significant difference with respect to free drug at the respective dose (p < 0.05). A † indicates significant difference with respect to blank particles (p < 0.05).
