Table 3.
A variety of liposome techniques employed for the encapsulation of polyphenols.
| Polyphenols | Applications | Biological activities | Loading | Route of administration | References |
|---|---|---|---|---|---|
| Curcumin | Photo-ageing attenuation (demonstration in mice) | Antioxidant, Anti-inflammatory Photo-protector | Oral | [112] | |
| Resveratrol | Improvement of the cellular answer to oxidative stress via rapid and potent cellular internalization. | Antioxidant Photo-protector | >70% | In vitro | [113] |
| Nano-sized vesicles, inclusion of resveratrol retarded drug release in vitro, this system was associated with no or poor liver and kidney toxicity in vivo. | Cardiovascular protector | ≈70% | In vitro and in vivo Intraperitoneal injection | [114] | |
| Quercetin | Reduced anxiety and cognitive functions, dose administered decrease, increase in circulation time, vectorization, increase in brain penetration efficiency. | Antioxidant, Anticancer | 60% | Nasal | [111] |
| Biodisponibility increased, vectorization, hepatic membrane penetration efficiency greatly improved. | Hepato-protector | Transdermic | [115] | ||
| Myrtle (Myrtus communis) extract | Antioxidant and antimicrobial activities superior to free forms. | Antioxidant, Antimicrobial | In vitro | [116] | |
| Thyme (Thymus sp.) extracts | [117] | ||||
| Silymarin | Biodisponibility increase. | Hepato-protector | >69% | Oral | [118] |
| Catechin | Skin penetration efficiency improved. | Chemo-protector, Antioxidant | >90% | Transdermic | [119] |
| Catechin, (-)-epicatechin and EGCG | Biodisponibility, EGCG encapsulated has tissue penetration ability improved versus 2 other catechins. | Antioxidant, Anticancer | Intratumoral | [106] | |
| Liposomes may influence drug deposition in tumor tissues. | Antioxidant, Anticancer | Topical application and intratumoral | [120] | ||
| Tea extract | Stability 4 °C increased. | Feasibility evaluation | In vitro | [121] |