Table 1.

Outcome of grinding experiments performed with Theophylline-Citric acid system. The data has been summarized from the work of Jones et al. [36].

Component 1	Component 2	Type of grinding	Product
TA	CA	Neat	AC
TA	CM	Neat	HC
TM	CA	Neat	HC
TM	CM	Neat	HC
TA, TM	CA, CM	Water-assisted	HC

TA: Theophylline Anhydrous; TM: Theophylline monohydrate; CA: Citric acid Anhydrous, CM: Citric acid monohydrate; AC: Anhydrous cocrystal, HC: Hydrated cocrystal.