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. 2011 Aug 31;3(3):601–614. doi: 10.3390/pharmaceutics3030601

Table 4.

Melting Point Comparison.

Salt (*) or Co-crystal M.P.of Co-crystallizing Agent M.P.of Salt(*)or Co-crystal M.P.of Diclofenac
(DC)·(3-aminopyridine)* 55–58 °C 108–112°C* 171–173 °C
(DC)·(2-aminopyridine)* 47–50 °C 73–74 °C* 171–173 °C
(DC)·(AMP) 151–153 °C 173–174 °C 171–173 °C
(DC)·(ACMP) 182–183 °C 169–172 °C 171–173 °C
(DC)·(3-hydroxypyridine) 126–129 °C 153–156 °C 171–173 °C
(DC)·(2-amino-4-hydroxy-6-methylpyrimidine) >300 °C >160 °C [sublimes] 171–173 °C
(DC)·(AP) 125–127 °C 168–172 °C 171–173 °C
(DC)·(4,4′-bipyridyl) 108–111 °C 155–157 °C 171–173 °C
(DC)·(2-amino-5-chloropyridine) 132–135 °C 150–154 °C 171–173 °C
(DC)·(4-chloro-2,6-diaminopyrimidine) 196–199 °C 155–160 °C 171–173 °C
(DC)·(2-amino-3,5-dibromopyridine) 98–100 °C 145–150 °C 171–173 °C