Skip to main content
. Author manuscript; available in PMC: 2013 Dec 9.
Published in final edited form as: Am J Physiol Gastrointest Liver Physiol. 2006 Aug;291(2):10.1152/ajpgi.00011.2006. doi: 10.1152/ajpgi.00011.2006

Table 1.

Body weights, relative organ weights, and plasma retinol concentrations in RA- and LPS-treated rats

Control RA LPS RA + LPS
BW at dosing, g 233.8±9.80 224.2±8.67 212.9±5.74 217.9±7.36
Change in BW, g/12 h −6.8±1.0 −6.4±0.9 −8.0±1.0 −8.2±1.0
Liver weight, % BW 3.64±0.06 3.76±0.12 3.91±0.11 4.03±0.10a
Lung weight, % BW 0.51±0.02 0.53±0.01 0.54±0.02 0.53±0.02
Spleen weight, % BW 0.22±0.01 0.22±0.01 0.27±0.01a,b 0.29±0.01a,b
Small intestine weight, % BW 2.29±0.09 2.41±0.09 2.43±0.13 2.43±0.14
Plasma retinol, µmol/l 0.54±0.06 0.44±0.06 0.30±0.04a,b 0.29±0.04a,b
Liver total retinol, nmol/g* 17±11 21±6 18±5 14±17
Total 3H-labeled retinoids, % ID 30.0±1.23 33.3±1.38 26.5±1.16b 28.1±1.15b

Values are means ± SE; n = 9/group. RA, retinoic acid; LPS, lipopolysaccharide; BW, body wt.

*

For liver total retinol, values are means ± range of two representative rats per group.

For total 3H-labeled retinoids, values are sums of plasma, liver, lung, and small intestine total 3H-labeled retinoids, expressed as percent injected dose (ID).

a

Statistically different from control rats (P < 0.05).

b

Statistically different from RA-treated rats (P < 0.05).