Table 1. Homozygous regions and candidate genes found in the studied families.

Family #	Chromosome	Length*	SNP/Mb	Start	Stop	RANK	Genes
PB15	15	8	97	94,755,230	103,000,000	1
	3	20	69	81,385,867	101,821,068	2	IMPG2, BBS3
	11	8	48	48,019,397	56,670,113	3
	8	6	18	42,604,791	49,328,524	4
PB74	7	2.8	192	14,305,994	17,109,926	1
	9	2.6	147	23,912,009	26,502,533	2
	11	25.2	110	8,268,949	33,487,251	3	TEAD1, USH1C
	6	2.4	104	75,641,951	78,011,282	4
	14	24.4	99	33,161,305	57,535,645	5	OTX2
	13	20	92	41,472,025	61,458,472	6	RB1
	2	11.3	77	229,188,012	240,448,167	7	SAG, KCNJ13
	3	30.2	73	86,088,197	116,313,537	8	IMPG2, BBS3
	1	2.9	47	49,428,303	52,348,388	9
	4	3.6	45	0	3,586,240	10	PDE6B
	11	5.6	42	51,538,030	57,168,706	11
	19	2.2	25	17,232,499	19,446,936	12
	10	5.6	24	37,264,807	42,897,610	13
RP290	4	22	111	164,572,108	1,886,612,779	1
	13	24	110	19,611,203	43,979,500	2
	4	17	109	14,126,510	31,208,706	3	PROM1
	14	18	95	72,775,668	90,693,572	4	BBS8
	11	37	78	27,547,379	64,200,379	5	BEST1, ROM1
	9	22	71	115,228,455	137,266,704	6
	11	16	51	64,202,427	80,653,055	7	BBS1, CABP4, EVR4, MYO7A
RP517	18	10	147	64,702,698	75,485,034	1
	10	15	104	102,878,609	124,720,093	2
	15	6	99	88,605,547	94,989,511	3	RLBP1
	4	27	93	142,603,130	170,091,790	4	LRAT
	6	5	93	134,536,698	139,731,589	5	AHI1, PEX7
	10	42	92	13,549,280	55,658,110	6	RBP3, PCDH15
	10	16	90	73,315,427	90,014,680	7	PCDH21, RGR
	2	19	88	215,924,486	243,717,669	8	SAG, KCNJ13
	2	7	85	161,288,182	168,767,322	9
	7	10	77	139,122,579	149,147,283	10
	16	22	68	54,368,954	76,163,081	11	CNGB1, CDH3
RP670	15	20	67	70,670,532	91,626,291	1	RLBP1, NR2E3
	12	5	35	33,095,301	38,783,937	2
	11	7	28	47,884,847	55,182,977	3
RP745	18	15	131	59,022,364	74,333,187	1
	7	13	96	36,733,691	49,999,517	2
	5	27	81	38,657,850	65,932,343	3
	7	32	74	70,138,345	102,504,683	4	PEX1
	7	20	61	50,006,472	70,113,409	5
	11	8	34	47,873,883	55,620,859	6
	17	17	33	14,152,804	30,823,007	7	HRG4/UNC119
RP819	16	7	145	6,137,184	12,877,511	1
	11	9	106	76,325,821	85,436,868	2	MYO7A
	3	17	93	100,042,849	116,695,553	3	IMPG2
	10	11	89	99,038,933	110,389,800	4	ARL3
	5	20	82	72,943,817	92,857,172	5
RP854	8	7	125	16,489,491	23,287,191	1
	12	6	113	102,972,070	108,720,576	2
	1	9	97	167,407,517	176,453,828	3
	8	24	98	102,458,515	126,789,312	4
	8	13	96	53,880,054	67,044,043	5	RP1, TTPA
	2	7	81	183,870,146	191,325,255	6
	2	8	74	26,097,607	34,429,224	7	ZNF513, C2ORF71
	5	16	67	38,414,330	54,391,555
RP855	11	12	119	85,869,911	97,383,737	1
	15	5	117	33,415,288	38,491,401	2
	10	19	114	105,391,725	123,911,345	3
	13	6	106	84,581,120	90,263,015	4
	6	8	104	117,641,016	125,607,559	5
	5	23	103	101,320,305	123,846,658	6
	7	15	103	155,645,303	170,683,241	7
	18	9	101	38,011,865	47,209,971	8
	5	5	101	26,045,009	31,423,339	9
	14	14	96	34,194,336	48,552,897	10
	4	25	93	111,252,455	136,022,295	11	BBS12
	11	10	89	110,685,226	120,548,318	12	MFRP
	2	16	88	148,875,566	164,388,639	13
	10	29	87	34,317,035	63,401,422	14	RBP3, PCDH15
	20	9	87	53,622,497	63,000,000	15	PRPF6
	6	20	84	23,895,019	44,154,325	16	TULP1, PRPH2
	21	5	73	42,506,107	48,000,000	17
	11	48	72	35,991,050	83,847,610	18	BEST1, ROM1, BBS1, CABP4, MYO7A
RP1013	7	15	112	19,386,915	34,648,783	1	KLHL7,PAP1
	5	15	110	106,422,649	121,734,393	2
	16	15	104	1,889,821	16,730,604	3	ABCC6
	8	7	103	25,445,326	32,079,101	4
	7	9	92	120,144,923	128,748,534	5	TSPAN12, IMPDH1, OPN1SW
	2	36	89	188,652,307	224,429,597	6
	8	11	86	58,758,850	69,756,364	7	TTPA
	3	53	85	68,243,465	121,132,268	8	BBS3, IMPG2
	8	30	85	73,152,837	102,974,357	9	PEX2, CNGB3, C8ORF37
	5	48	84	26,788,362	74,365,757	10
	7	10	81	137,476,571	147,969,602	11
	11	48	70	32,076,832	80,155,054	12	BEST1, ROM1, BBS1, LRP5
	2	11	68	23,712,008	34,302,743	13	ZNF513, C2ORF71
RP1077	1	25	106	217,257,837	241,982,430	1
	21	21	98	9,764,385	31,185,292	2
	4	5	20	48,094,534	53,233,482	3
	5	6	16	44,334,983	50,066,049	4
	20	5	10	25,506,582	30,680,225	5
	16	15	4	31,905,355	46,831,180	6
	2	7	3	88,965,501	96,239,773	7
	9	33	2	38,703,364	71,244,025	8
RP1324	16	7	100	54,776,161	62,457,005	1	CNGB1, BBS2
RP1361	5	16	112	145,313,228	162,831,477	1	PDE6A
	20	11	112	49,172,235	60,352,153	2
	16	16	107	65,223,172	81,678,049	3	OPA8, CDH3
	8	25	77	37,328,843	63,110,766	4	RP1, ADAM9
	20	22	66	22,782,904	45,359,408	5
RP1625	8	18	142	5,057,818	23,559,224	1	RP1L1
	1	13	120	58,394,231	72,327,802	2	RPE65
	4	5	98	31,636,008	36,732,290	3
	7	7	91	123,580,016	131,407,605	4	OPN1SW, IMPDH1
	12	13	90	117,118,028	130,497,472	5
	2	7	79	233,929,283	241,117,231	6	SAG
	8	32	79	40,071,825	72,824,945	7	RP1, TTPA
	12	5	30	34,142,799	39,744,369	8
	3	5	27	88,365,050	93,558,926	9
	7	7	17	56,665,370	63,796,171	10
RP1682	15	13	89	81,632,077	95,169,873	1	RLBP1
	5	5	74	172,682,382	177,906,494	2

For each family, homozygous regions were classified according to the size of the region in Mb, and the coverage (number of SNP per Mb) to give a rank for prioritizing the molecular screening. Each region is then defined by its position on the corresponding chromosome (Start and Stop sections). The causative gene was bolded for families with positive molecular diagnosis. *: In Megabase pair.