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. 2013 Dec 9;8(12):e75600. doi: 10.1371/journal.pone.0075600

Figure 10. Effect of exogenous TGFβ-1 on α-smooth muscle actin-(SMA) expression and cellular organisation.

Figure 10

A. Elevated α-SMA protein expression and cellular re-organisation into whirl-like structures were observed in PKF upon 24 hrs treatment with 1 ng/mL TGFβ-1. B. Elevated α-SMA expression and incorporation into microfilaments was observed in NF treated with 1 ng/mL TGFβ-1, although no cellular re-organisation was noted. Blue = nuclei, Green = α-SMA protein, NF = normal dermal fibroblasts (n = 4), PKF = peri-lesional keloid fibroblasts (n = 5).