Figure 2. NF-κB activity and iNOS expression in both wt and mdx myotubes.

A. NF-κB activity was studied with a luciferase reporter. Nifedipine treatment (10 µM for 6 h) reduced NF-κB activity in mdx, without any significant effect in wt myotubes (n = 6–12). B. mRNA levels of iNOS were determined by real time PCR after 6 h of nifedipine treatment (10 µM) (n = 6–7). Data are expressed as mean ± S.E.M., *P<0.05, **P<0.01, ***P<0.001, ANOVA-Tukey’s.