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. 2013 Dec 9;8(12):e81220. doi: 10.1371/journal.pone.0081220

Figure 10. Interplay between PKA pathway and Notch1 pathway.

Figure 10

(A). Effect of H-89 on VEGF-induced expression of Cleaved Notch1. (B). Quantification of Cleaved Notch1 expression. (C). Effect of H-89 on VEGF-induced HEY1 and HEY2 gene expressions. (D). Quantification of HEY1 and HEY2 gene expressions. (E). Effect of DAPT on VEGF-induced phosphorylation of PKA. (F). Quantification of PKA phosphorylation. The data were expressed as mean ± SD of three independent experiments. # P<0.05 vs. normal group; *P<0.05, **P<0.01 vs. VEGF group. NOR, norisoboldine; Cur, curcumin.