Figure 6. Abundance of SIV-specific CD8 T cells in lymphoid and genital tissues.

The number of MHC-tetramer⁺ cells per mm² in lymphoid tissues is presented in panels A) and B) and in the lamina propria of genital tissues in panels C) and D). The tissue density of Mamu-A1/Tat stained cells are shown in A) and C), and Mamu-A1/Gag stained cells shown in B) and D). Animal numbers, days post-SIVΔnef vaccination (dpv) and days post-challenge (dpc) are indicated below each graph. Negative control sections stained with Mamu-A1/FLP showed a range of 0-3.4 cells/mm² and average of 1.25 cells/mm² in lymphoid tissues, and 0 cells/mm² in the genital tissues.