(A) Opacification, vascularization, and edema were monitored every three days by two independent investigators. A significant difference in opacification between the miglyol and AZM allogen group could be detected at day 3 (p < 0.05), day 9 (p < 0.01) and at day 12 (p < 0.001) after keratoplasty. No significant difference between AZM syngeneic (group 3) and allogeneic (group 2) could be detected. Vascularization was not influenced in all groups.
(B) Vascularization was not affected by AZM compared to controls.
(C) Corneal edema was reduced in the AZM allogen group compared to the miglyol group beginning at day 9 (p < 0.05). A representative photo on day 12 following keratoplasty is shown. Bars show group 4 (control, black) in comparison with group 2 (grey) and group 3 (control, light grey) with SEM.