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. 2013 Dec 9;8(12):e82687. doi: 10.1371/journal.pone.0082687

Figure 4. Immunohistological analysis of leukocytic infiltration.

Figure 4

(A) Immunostainings on cryosections of miglyol-treated (group 4, black) and AZM-treated animals (group 2, light grey; group 3, dark grey) were performed on day 13. Infiltrating CD45+ leukocytes in group 2 were significantly reduced in comparison to group 4 (p<0.01). Red cells are positive for the antibody.

(B) While no difference in the number of CD4+ T cells was seen in both groups, the infiltrating CD8+ T cells (p < 0.05) and CD25+ T cells (p < 0.05) were reduced significantly in the AZM-treated animals.

(C) The number of infiltrating CD161+ NK cells (p < 0.05) and of CD163+ macrophages (p < 0.05) in the central corneal stroma was significant reduced.