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. 2013 Dec 9;8(12):e82687. doi: 10.1371/journal.pone.0082687

Figure 5. Short-time treatment with AZM.

Figure 5

(A) A reduced treatment regimen with seven days in total (three days prior to transplantation and three days following keratoplasty) in group 6 improved graft survival significantly compared to controls in group 7 (p < 0.05). Rejection occurred in miglyol-treated rats at day 14 [12.3–15.2], whereas in the AZM-treated group, rejection occurred at day 30 [22.2–38.1].

(B) Even only a three-day preoperative treatment with AZM (group 8) improved graft survival significantly compared with controls with miglyol (group 9; p < 0.05). Rejection occurred in group 9 at day 13 [13.0–14.4], whereas in group 8, rejection occurred at day 26 [18. –33.7].