Table 1.
Type of IUD | Number of subjects | Time of insertion | Significant event rate | Comments | Study |
---|---|---|---|---|---|
121 | 6–8 weeks | Expulsion 28.3*,e Controls expulsion 11.8% |
Prospective, cumulative per 100 woman yearsa | Wiese5 | |
318 | 6 weeks+ | Nil | Retrospective pooled Controlledb | Chi and Balogh6 | |
Cu-T 200 | 107 | 6 weeks | Expulsion 6.5%* Removals 8.4%* |
Prospective controlled %, not life tablec | Gupta et al7 |
215 | 6 weeks+ | Expulsion 19e | Retrospective cumulative rate, non-controlledd | Holloway et al8 | |
Szontagh IUD | 288 | Interval | Expulsion elevated (rate not specified)a | Controlled prospective cumulative rates not expressed | Chi et al9 |
400 | Interval | Pregnancy□ Removal⋄ Expulsion• VCu 200 0% TCu 380A 3.1%a |
Prospective controlled VCu vs TCu 380A Event rates for both devices within accepted limits Not cumulative |
Tang and Feng10 | |
Cu-T 200 | 45 | Interval | Expulsion 8.8%a | Not life-table1 perforation not controlled | Parikh and Gandhi11 |
Notes:
P<0.05 for study group versus control group;
P<0.05 for VCu (1.02%) versus TCu 380A (4.64%);
P<0.05 for VCu (1.02%) versus TCu 380A (4.13%);
P<0.05 for VCu (0%) versus TCu 380A (3.1%);
12 month follow up;
6 month follow up;
24 month follow up;
48 month follow up;
per 100 women years of use. Antigon (Svend Schroeder Co., Copenhagen, Denmark); Lippes Loop (Ortho Pharmaceutical, Raritan, NJ, USA); Dalkon shield (AH Robbins, Richmond, VA, USA); MLCu (Prosan S.A. Arnham, the Netherlands); Copper 7® (G.D.Searle and Co., High Wycombe, England, UK); Copper-T® (Ortho Pharmaceutical); Szontagh IUD (Semmelweiss University, Budapest, Hungary); VCu (Dr Y. Wu, Shanghai, People’s Republic of China); TCu 380A (Teva Pharmaceutical Industries Ltd., Petach Tikva, Israel); Copper T 200 originally marketed by Ortho Pharmaceuticals, now replaced by TCU 380A of Teva Pharmaceutical Industries Ltd.
Abbreviation: IUD, intrauterine device; vs, versus.