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. 2013 Dec 9;8(12):e82928. doi: 10.1371/journal.pone.0082928

Table 2. Dry weight of iron from the liver and the heart tissues of mice.

Dry weight of Iron (µg/gm)
Liver tissue Heart tissue
Normal levels 101.3 ± 19.1 57.2 ± 41.6
Iron overloaded mice (Group 1) 11945 ± 2253 389 ± 188
Iron overloaded and deferiprone treated mice (Group 2) 9319 ± 2865 138 ± 66*
Iron overloaded and hydroxyurea treated mice (Group 3) 10316 ± 2820 150 ± 128*
Iron overloaded and deferasirox treated mice (Group 4) 11135 ± 1878 171 ± 98*
Iron overloaded and deferiprone and hydroxyurea treated mice (Group 5) 7136 ± 1631* 208 ± 200*
Iron overloaded and hydroxyurea and deferasirox treated mice (Group 6) 7397 ± 1570* 159 ± 141*
Iron overloaded and deferiprone and deferasirox treated mice (Group 7) 6339 ± 934* 97 ± 69*
Iron overloaded and deferiprone, deferasirox and hydroxyurea treated mice (Group 8) 6739 ± 1764* 89 ± 60*

* Statistically significant reduction (p<0.001) in dry weight of liver or heart iron of the particular group compared to the group 1