Table.
Demographics and Clinical Characteristics of the Study Population
| Characteristics | No. (%)a | P Valueb | |||||
|---|---|---|---|---|---|---|---|
| IMRT (n = 23 633) | EBRT (n = 3926) | Robotic Prostatectomy (n = 5881) | Open Radical Prostatectomy (n = 6123) | Observation (n = 16 384) | |||
| Age, y 66–69 |
5536 (23) |
978 (25) |
3334 (57) |
3479 (57) |
3766 (23) |
|
<.001 |
| 70–74 | 8540 (36) | 1409 (36) | 2071 (35) | 2174 (36) | 4557 (28) | ||
| 75–79 | 6670 (28) | 1063 (27) | 438 (7) | 437 (7) | 4086 (25) | ||
| >80 | 2887 (12) | 476 (12) | 38 (<1) | 33 (<1) | 3975 (24) | ||
| Race/ethnicity White |
19 232 (81) |
3207 (82) |
5056 (86) |
5238 (86) |
13 236 (81) |
|
<.001 |
| Black | 2508 (11) | 454 (12) | 349 (6) | 461 (8) | 2044 (12) | ||
| Hispanic | 498 (2) | 96 (2) | 66 (1) | 127 (2) | 306 (2) | ||
| Asian | 700 (3) | 100 (3) | 152 (3) | 114 (2) | 412 (3) | ||
| Other | 695 (3) | 69 (2) | 258 (4) | 183 (3) | 386 (2) | ||
| Socioeconomic class Low |
6151 (26) |
1390 (35) |
1289 (22) |
1703 (28) |
4889 (30) |
|
<.001 |
| Medium | 10 305 (44) | 1372 (35) | 1843 (31) | 1930 (32) | 5836 (36) | ||
| High | 7177 (30) | 1164 (30) | 2749 (47) | 2490 (41) | 5659 (35) | ||
| Comorbidity score 0 |
14 612 (62) |
2415 (62) |
4501 (77) |
4537 (74) |
10 830 (66) |
|
<.001 |
| 1 | 5697 (24) | 992 (25) | 1048 (18) | 1214 (20) | 3241 (20) | ||
| 2 | 2019 (9) | 324 (8) | 243 (4) | 265 (4) | 1313 (8) | ||
| ≥3 | 1305 (6) | 195 (5) | 89 (2) | 107 (2) | 1000 (6) | ||
| Tumor grade Well or moderately differentiated |
8482 (36) |
1260 (32) |
1971 (34) |
2276 (37) |
10 565 (64) |
|
<.001 |
| Poorly differentiated or undifferentiated | 15 151 (64) | 2666 (68) | 3910 (66) | 3847 (63) | 5819 (36) | ||
| Clinical stage T1 |
13 080 (55) |
1923 (49) |
3551 (60) |
3099 (51) |
9611 (59) |
|
<.001 |
| T2 | 9614 (41) | 1809 (46) | 2237 (38) | 2867 (47) | 6571 (40) | ||
| T3/T4 | 939 (4) | 194 (5) | 93 (2) | 157 (3) | 202 (1) | ||
| Disease risk classification Low |
6266 (27) |
785 (20) |
1663 (28) |
1730 (28) |
8871 (54) |
|
<.001 |
| Intermediate | 8870 (38) | 1427 (36) | 3022 (51) | 2765 (45) | 4618 (28) | ||
| High | 8497 (36) | 1714 (44) | 1196 (20) | 1628 (27) | 2895 (18) | ||
| Risk of noncancer mortality Low |
6644 (28) |
1015 (26) |
3169 (54) |
3078 (50) |
4113 (25) |
|
<.001 |
| Intermediate | 8307 (35) | 1417 (36) | 2058 (35) | 2276 (37) | 4977 (30) | ||
| High | 8682 (37) | 1494 (38) | 654 (11) | 769 (13) | 7294 (45) | ||
| Year of diagnosis 2004 |
2990 (13) |
1618 (41) |
432 (7) |
1516 (25) |
2624 (16) |
|
<.001 |
| 2005 | 3609 (15) | 927 (24) | 614 (10) | 1219 (20) | 2661 (16) | ||
| 2006 | 4237 (18) | 613 (16) | 906 (15) | 1056 (17) | 2889 (18) | ||
| 2007 | 4569 (19) | 415 (11) | 1191 (20) | 976 (16) | 2893 (18) | ||
| 2008 | 4195 (18) | 191 (5) | 1345 (23) | 775 (13) | 2737 (17) | ||
| 2009 | 4033 (17) | 162 (4) | 1393 (24) | 581 (9) | 2580 (16) | ||
| SEER regionc San Francisco |
715 (3) |
216 (6) |
216 (4) |
190 (3) |
748 (5) |
|
<.001 |
| Connecticut | 1766 (7) | 196 (5) | 303 (5) | 187 (3) | 1011 (6) | ||
| Detroit (Metropolitan) | 2046 (9) | 369 (9) | 479 (8) | 257 (4) | 1243 (8) | ||
| Hawaii | 470 (2) | 35 (1) | 137 (2) | 47 (1) | 186 (1) | ||
| Iowa | 1168 (5) | 337 (9) | 286 (5) | 513 (8) | 750 (5) | ||
| New Mexico | 627 (3) | 44 (1) | 87 (1) | 268 (4) | 588 (4) | ||
| Seattle (Puget Sound) | 1110 (5) | 271 (7) | 406 (7) | 625 (10) | 1338 (8) | ||
| Utah | 214 (<1) | 250 (6) | 121 (2) | 421 (7) | 653 (4) | ||
| Atlanta (Metropolitan) | 1002 (4) | 128 (3) | 69 (1) | 94 (2) | 535 (3) | ||
| San Jose | 629 (3) | 96 (2) | 110 (2) | 111 (2) | 457 (3) | ||
| Los Angeles | 1529 (6) | 141 (4) | 719 (12) | 600 (10) | 1185 (7) | ||
| Greater California | 3733 (16) | 630 (16) | 1468 (25) | 1536 (25) | 3423 (21) | ||
| Kentucky | 1276 (5) | 489 (12) | 518 (9) | 353 (6) | 1187 (7) | ||
| Louisiana | 1810 (8) | 220 (6) | 296 (5) | 497 (8) | 1094 (7) | ||
| New Jersey | 5466 (23) | 475 (12) | 658 (11) | 418 (7) | 1948 (12) | ||
Abbreviations: EBRT, traditional external beam radiation treatment; IMRT, intensity-modulated radiotherapy; SEER, Surveillance, Epidemiology, and End Results.
a
Percentages might not sum to 100 because of rounding.
b
P values generated from χ2 tests.
c
Data not shown for 153 patients in the SEER Rural Georgia registry according to SEER-Medicare guidelines.