Table 2.
Treated group | Week 0 | Week 24 | ||||
---|---|---|---|---|---|---|
Score type | n | Median | Interquartile Range | Median | Interquartile Range | P-Value |
Steatosis* | 14 | 2 | (1, 4) | 1 | (0, 2) | 0.164 |
Inflammation* | 14 | 1 | (1, 2) | 1 | (1, 2) | 0.480 |
Necrosis | 14 | 0 | (0, 0) | 0 | (0, 0) | 0.079 |
Fibrosis* | 14 | 3 | (2, 4) | 3 | (2, 4) | 0.962 |
TUNEL stain | 14 | 8 | (6, 17) | 8.5 | (2, 16) | 0.661 |
Percent fibrosis per square field* | 14 | 4 | (2.69, 8.37) | 6.57 | (2.80, 11.76) | 0.597 |
Smooth muscle actin stain | 14 | 2 | (1, 3) | 1 | (0, 2) | 0.027 |
Kupffer | 14 | 1 | (0, 2) | 0.5 | (0, 1) | 0.474 |
PMN | 14 | 0 | (0, 1) | 0 | (0,1) | 0.978 |
Lipogranules | 14 | 0 | (0, 0) | 0 | (0, 0) | 0.970 |
Lymphocytes | 14 | 1 | (0, 2) | 1 | (1, 1) | 0.960 |
Balloon cells | 14 | 0 | (0, 1) | 1 | (0, 1) | 0.548 |
Mallory-Denk bodies* | 14 | 1 | (0, 3) | 1 | (0, 2) | 0.473 |
Duct metaplasia | 14 | 3 | (2, 4) | 2 | (2, 4) | 0.701 |
Denotes score types previously reported by Medici et al., 2011; however, now the treatment and placebo scores are combined