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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Exp Mol Pathol. 2013 Jul 23;95(2):10.1016/j.yexmp.2013.07.003. doi: 10.1016/j.yexmp.2013.07.003

Table 2.

Scores are expressed as Median and interquartile range (25th, 75th percentile). P-values are calculated by Mann-Whitney Rank Sum Test were P<0.05 indicates a statistically significant difference in the median values between the two groups and P>=0.05 indicates the difference in the median values between the two groups is not great enough to exclude the possibility that the difference is due to random sampling variability. Smooth muscle actin stain decreased at week 24

Treated group Week 0 Week 24
Score type n Median Interquartile Range Median Interquartile Range P-Value
Steatosis* 14 2 (1, 4) 1 (0, 2) 0.164
Inflammation* 14 1 (1, 2) 1 (1, 2) 0.480
Necrosis 14 0 (0, 0) 0 (0, 0) 0.079
Fibrosis* 14 3 (2, 4) 3 (2, 4) 0.962
TUNEL stain 14 8 (6, 17) 8.5 (2, 16) 0.661
Percent fibrosis per square field* 14 4 (2.69, 8.37) 6.57 (2.80, 11.76) 0.597
Smooth muscle actin stain 14 2 (1, 3) 1 (0, 2) 0.027
Kupffer 14 1 (0, 2) 0.5 (0, 1) 0.474
PMN 14 0 (0, 1) 0 (0,1) 0.978
Lipogranules 14 0 (0, 0) 0 (0, 0) 0.970
Lymphocytes 14 1 (0, 2) 1 (1, 1) 0.960
Balloon cells 14 0 (0, 1) 1 (0, 1) 0.548
Mallory-Denk bodies* 14 1 (0, 3) 1 (0, 2) 0.473
Duct metaplasia 14 3 (2, 4) 2 (2, 4) 0.701
*

Denotes score types previously reported by Medici et al., 2011; however, now the treatment and placebo scores are combined