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. 2013 Dec 9;203(5):717–725. doi: 10.1083/jcb.201307100

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© 2013 Godlee and Kaksonen

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Figure 1. — Examples of regulation of the initiation of endocytosis. (A) In yeast Saccharomyces cerevisiae, clathrin-mediated endocytosis is polarized to the growing bud. (B) After signal propagation at the synapse, exocytosis of the neurotransmitter is accompanied by a compensatory increase in clathrin-mediated endocytosis to maintain synaptic plasma membrane area and recycle synaptic vesicle components. (C) Many viruses enter the host cell by clathrin-mediated endocytosis. The virus particle may exploit the cell’s regulation of endocytosis in order to induce its own uptake.