Table 1.
Point estimation |
Interval estimation |
|||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cen | One-step, (1) |
Proposed, |
Jin et al. |
SW | TI | |||||||||
(%) | B | SD | Ω | B | SD | Ω | B | SD | Ω | SE | C | SE | C | |
size=100, 2 covariates | ||||||||||||||
0 | G | −2 | 124 | 5764 | 0 | 124 | 37 | 0 | 124 | 68 | 121 | 93.6 | 120 | 93.3 |
L | −7 | 108 | 106970 | −1 | 107 | 1105 | −1 | 107 | 3328 | 113 | 94.2 | 104 | 93.6 | |
25 | G | 5 | 151 | 6121 | 6 | 151 | 36 | 6 | 151 | 68 | 159 | 96.1 | 150 | 95.4 |
L | 0 | 138 | 59858 | 5 | 136 | 800 | 4 | 136 | 2767 | 146 | 95.1 | 132 | 94.8 | |
50 | G | 2 | 206 | 39234 | 10 | 201 | 45 | 10 | 201 | 97 | 230 | 96.7 | 204 | 95.3 |
L | 4 | 180 | 51839 | 10 | 179 | 1123 | 10 | 179 | 3839 | 204 | 96.3 | 177 | 94.6 | |
size=100, 4 covariates | ||||||||||||||
0 | G | −5 | 117 | 19449 | −3 | 117 | 93 | −3 | 117 | 235 | 123 | 95.3 | 119 | 94.8 |
L | −8 | 107 | 317532 | −2 | 103 | 3608 | −2 | 103 | 10735 | 119 | 97.1 | 103 | 94.8 | |
25 | G | −6 | 153 | 20245 | −4 | 153 | 107 | −4 | 153 | 273 | 159 | 95.1 | 148 | 94.2 |
L | −7 | 137 | 240739 | −2 | 136 | 9496 | −2 | 136 | 10739 | 160 | 95.6 | 127 | 93.3 | |
50 | G | −9 | 206 | 81991 | 1 | 200 | 173 | 1 | 200 | 435 | 227 | 95.3 | 198 | 94.2 |
L | −4 | 177 | 218665 | 4 | 175 | 11634 | 4 | 176 | 22207 | 217 | 96.4 | 166 | 93.2 | |
size=200, 2 covariates | ||||||||||||||
0 | G | −3 | 83 | 1789 | −3 | 83 | 5 | −3 | 83 | 9 | 83 | 94.5 | 83 | 94.2 |
L | −5 | 73 | 38260 | −3 | 72 | 314 | −3 | 72 | 1031 | 75 | 95.1 | 72 | 94.6 | |
25 | G | 3 | 103 | 1446 | 4 | 103 | 4 | 4 | 103 | 9 | 107 | 95.9 | 104 | 95.7 |
L | 4 | 91 | 20787 | 6 | 91 | 235 | 6 | 91 | 721 | 96 | 96.5 | 92 | 95.9 | |
50 | G | −4 | 141 | 14739 | −1 | 138 | 5 | −1 | 138 | 11 | 150 | 95.8 | 138 | 94.6 |
L | −1 | 120 | 22293 | 2 | 120 | 292 | 2 | 120 | 1548 | 131 | 96.4 | 120 | 95.8 | |
size=200, 4 covariates | ||||||||||||||
0 | G | 2 | 87 | 4329 | 2 | 87 | 12 | 2 | 87 | 29 | 84 | 93.7 | 83 | 93.6 |
L | −4 | 75 | 123051 | −1 | 75 | 890 | −1 | 75 | 2824 | 79 | 94.9 | 73 | 94.2 | |
25 | G | 2 | 101 | 4717 | 2 | 100 | 14 | 2 | 100 | 35 | 107 | 96.0 | 103 | 95.6 |
L | 1 | 89 | 111116 | 5 | 88 | 1146 | 5 | 88 | 3957 | 98 | 96.8 | 89 | 95.0 | |
50 | G | −1 | 136 | 18448 | 2 | 134 | 19 | 2 | 134 | 51 | 147 | 96.7 | 136 | 95.1 |
L | −1 | 113 | 112253 | 4 | 112 | 1592 | 4 | 112 | 5194 | 132 | 96.6 | 115 | 95.0 |
cen: censoring rate.
G: Gehan estimating function; L: log-rank estimating function.
With the log-rank function, Jin et al. was the estimator with 10 iterations.
For interval estimation, SW: the sandwich variance estimation; TI: the test inversion.
B, SD, SE, and C are all for the first coefficient, where B is bias (×103), SD standard deviation (×103),
SE mean standard error (×103), and C coverage (%) of the 95% confidence interval.
Ω: Mean quadratic score statistic (×106).