. Author manuscript; available in PMC: 2015 Jan 1.

Published in final edited form as: J Nutr Biochem. 2013 Oct 10;25(1):10.1016/j.jnutbio.2013.09.003. doi: 10.1016/j.jnutbio.2013.09.003

Table 1.

In vivo Cyp27B1 induction during acute and chronic inflammation.

Stimuli	Route of Administration	Genotype	Tissues	Cyp27B1 Induction^†
LPS	Intraperitoneal	Cyp KO	Liver, lung	0/9 (0%)
α-Galactosylceramide	Intraperitoneal	Cyp KO	Liver	0/6 (0%)
*L. monocytogenes*	Intraperitoneal	Cyp KO	Spleen	0/2 (0%)
DSS	Oral	Cyp KO	Intestines	6/22 (27%)
*S. rectivirgula*	Intranasal	Cyp KO	Lung	0/15 (0%)
*S. rectivirgula*	Intranasal	DKO	Lung	3/8 (38%)
Piroxicam	Oral	DKO	Intestines	3/9 (33%)

¹Cyp KO and IL-10/Cyp DKO mice were exposed to various stimuli to elicit inflammation in different tissues.

² The ratio of the number of mice showing β-galactosidase staining in the tissue per numbers of mice tested.