Table 1. Comprehensive list of tunable mechanical properties of engineered collagen matrices.
Design | Collagen Concentration | Crosslinked | Layers | Ultimate Tensile Strength (MPa) | Strain at failure (%) | Young's Modulus (MPa) | Resilience (%) | Thickness (μm) |
---|---|---|---|---|---|---|---|---|
1 | 0.625 | Yes | 1 | 5.22 ± 1.54 | 11.8 ± 2.33 | 57.2 ± 13.2 | 93.0 ± 3.77 | 10.5 ± 1.74 |
2 | 0.625 | Yes | 2 | 10.5 ± 1.07 | 12.1 ± 2.93 | 114 ± 15.2 | 93.1 ± 2.56 | 16.5 ± 1.93 |
3 | 0.625 | Yes | 4 | 9.46 ± 1.23 | 15.6 ± 2.27 | 94.8 ± 15.8 | 93.8 ± 3.31 | 30.2 ± 2.78 |
4 | 1.25 | Yes | 1 | 4.72 ± 1.01 | 9.29 ± 2.31 | 62.8 ± 13.8 | 96.6 ± 1.36 | 20.5 ± 5.65 |
5 | 2.5 | Yes | 1 | 5.11 ± 1.24 | 12.5 ± 1.91 | 59.4 ± 8.19 | 96.1 ± 1.67 | 35.5 ± 2.26 |
6 | 2.5 | Yes | 2 | 8.03 ± 0.49 | 10.8 ± 0.91 | 106 ± 9.22 | 97.8 ± 1.26 | 63.0 ± 2.47 |
7 | 2.5 | Yes | 4 | 8.17 ± 0.53 | 13.0 ± 0.96 | 93.3 ± 4.03 | 98.6 ± 0.26 | 124 ± 2.42 |
8 | 5 | Yes | 1 | 4.86 ± 1.32 | 15.4 ± 2.73 | 52.0 ± 16.5 | 98.7 ± 1.45 | 76.4 ± 5.21 |
9 | 0.625 | No | 1 | 0.75 ± 0.09 | 40.4 ± 4.35 | 1.99 ± 0.24 | 57.9 ± 16.7 | 10.1 ± 0.81 |
10 | 0.625 | No | 2 | 1.63 ± 0.38 | 38.9 ± 5.29 | 6.27 ± 1.57 | 60.0 ± 12.7 | 16.8 ± 1.13 |
11 | 0.625 | No | 4 | 1.55 ± 0.29 | 38.4 ± 6.35 | 6.10 ± 0.99 | 57.7 ± 5.66 | 30.6 ± 1.87 |
12 | 1.25 | No | 1 | 0.80 ± 0.11 | 47.6 ± 6.72 | 2.24 ± 0.69 | 73.6 ± 9.50 | 23.6 ± 1.99 |
13 | 2.5 | No | 1 | 0.71 ± 0.06 | 37.1 ± 2.21 | 2.09 ± 0.42 | 58.9 ± 4.43 | 37.8 ± 3.09 |
14 | 2.5 | No | 2 | 1.62 ± 0.40 | 36.9 ± 12.5 | 5.22 ± 0.48 | 63.9 ± 2.62 | 65.3 ± 2.01 |
15 | 2.5 | No | 4 | 1.45 ± 0.23 | 36.9 ± 3.24 | 4.48 ± 0.58 | 61.8 ± 3.65 | 116 ± 5.69 |
16 | 2.5 | No | 12 | 1.77 ± 0.32 | 34.4 ± 3.89 | 6.18 ± 1.45 | 67.9 ± 2.30 | 368 ± 16.5 |
17 | 5 | No | 1 | 0.57 ± 0.09 | 38.6 ± 10.3 | 2.15 ± 0.730 | 66.7 ± 4.91 | 73.1 ± 4.56 |
Data is represented at mean ± S.D. for 4 representative samples.