Figure 1.

(a) A schematic of a network of neurons. Primary cilia (red) protrude from the neuronal cell body. (b) A schematic of a neuronal primary cilium. GPCRs selectively localize to the membrane of the cilium where they may reside as monomeric units and/or heteromers. An intraflagellar transport particle that mediates protein trafficking within cilia is indicated in green. (c) A hypothalamic neuron labeled for the ciliary GPCR, melanin-concentrating hormone receptor 1 (Mchr1, green). Scale bar=10 mm.