Table 3. Differentially Regulated Proteins in Plasma During Cocaine Withdrawal.

Gene name	Type	Gel spot no	Fold change	t-test (p-value)
Apolipoprotein A-ll	Transporter	1537	−1.2	0.012
Coiled-coil-helix-coiled-coil-helix domain 1	Other	63	1.42	0.014
Clusterin	Apoptosis	1469	−2.42	0.049
Fibronectin1 isoform 6 preproprotein	Enzyme	87	1.59	0.0029
Fibronectin1 isoform4 preproprotein	Enzyme	88	1.75	0.018
Fibronectin1 isoform 1 preproprotein	Enzyme	89	1.68	0.0028
Vitamin D-binding protein	Transporter	1320	−1.59	0.054
GDP dissociation inhibitor 1	Brain: GTPase activation	84	1.54	0.0032
GDNF-inducible zinc finger protein 1	Transcriptional regulation	599	−1.3	0.024
Heat shock 70 kDa protein 9 (mortalin)	Protein exportfrom nucleus	610	−1.28	0.044
Interleukin 13	Cytokine	652	−3.83	0.048
Kininogen 1	Receptor binding	608	−1.56	0.016
Phospholipase D1, phosphatidylcholine-specific	Enzyme	560	1.12	0.077
Peroxisome proliferator-activated receptor α	Ligand-dependent nuclear receptor	762	−2.14	0.014
Serine peptidase inhibitor, clade B,member 6b	Peptidase activity	1444	3.3	0.076
S1 RNA binding domain 1	Other	791	−1.41	0.052
TBC1 domain family, member 8B	Regulation of Rab GTPase activity	104	1.57	0.091
Vacuolar protein sorting 28 homolog	Transporter	859	2.41	0.056
Vitronectin	Other	627	−1.34	0.026
21 nc finger protein 161 homolog	Transcriptional regulation	338	1.19	0.08

Gel spot numbers correspond with numbered spots identified/highlighted in Figure 5.