Table 4.
FcMRI clusters for Analysis 2: LIFG seed
| TD Group | ASD Group | Group comparison | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Peak location (Brodmann area) | Talairach coordinates | Peak location (Brodmann area) | Talairach coordinates | Peak location (Brodmann area) | Talairach coordinates | ||||||||||||
| Additional regions (% volume of cluster) | Volume | Additional regions (% volume of cluster) | Volume | Additional regions (% volume of cluster) | Volume | ||||||||||||
| x | y | z | μl | t-value | x | y | z | μl | t-value | x | y | z | μl | t-value | |||
| L inferior frontal gyrus (p. Triangularis) (44/45) | -51 | 15 | 22 | 53384 | 32.7 | L inferior frontal gyrus (p. Triangularis) (44/45) | -45 | 23 | 22 | 231016 | 29.0 | ASD > TD | |||||
| L inferior frontal gyrus (p. Triangularis) (24.9%) | L inferior frontal gyrus (p. Triangularis) (5.6%) | L lingual gyrus (18) | -5 | -45 | 0 | 74040 | 5.6 | ||||||||||
| L middle frontal gyrus (7.9%) | L middle temporal gyrus (4.7%) | L middle temporal gyrus (7.6%) | |||||||||||||||
| L inferior frontal gyrus (p. Opercularis) (7.7%) | L precentral gyrus (3.3%) | R fusiform gyrus (4.9%) | |||||||||||||||
| L precentral gyrus (7.3%) | R inferior frontal gyrus (p. Triangularis) (3.1%) | L inferior temporal gyrus (4.9%) | |||||||||||||||
| L middle temporal gyrus (5.1%) | L middle occipital gyrus (2.6%) | L lingual gyrus (4.4%) | |||||||||||||||
| L caudate nucleus (5.1%) | R inferior frontal gyrus (p. Opercularis) (2.5%) | L calcarine gyrus (3.1 %) | |||||||||||||||
| L thalamus (4.2%) | R precentral gyrus (2.5%) | L hippocampus (3.0%) | |||||||||||||||
| L insula lobe (4.2%) | L inferior frontal gyrus (p. Opercularis) (2.4%) | R inferior temporal gyrus (3.0%) | |||||||||||||||
| L inferior frontal gyrus (p. Orbitalis) (3.7%) | L middle frontal gyrus (2.1%) | L fusiform gyrus (2.8%) | |||||||||||||||
| R inferior frontal gyrus (p. Triangularis) (45) | 41 | 23 | 28 | 10272 | 12.2 | R cerebellum (Crus 1) (2.1%) | R lingual gyrus (2.8%) | ||||||||||
| R inferior frontal gyrus (p. Triangularis) (34.8%) | L thalamus (2.1%) | R cerebellum IV-V (2.5%) | |||||||||||||||
| R inferior frontal gyrus (p. Opercularis) (12.4%) | R thalamus (2.0%) | L insula lobe (2.2%) | |||||||||||||||
| R precentral gyrus (9.3%) | R calcarine gyrus (17) | 17 | -59 | 4 | 856 | 9.8 | L middle frontal gyrus (2.2%) | ||||||||||
| R postcentral gyrus (9.3%) | R fusiform gyrus (20) | 39 | -17 | -24 | 736 | 12.3 | L precentral gyrus (2.1%) | ||||||||||
| R insula lobe (6.9%) | L cerebellum (Crus 1) | -17 | -71 | -26 | 400 | 8.6 | L putamen (2.1%) | ||||||||||
| R middle frontal gyrus (3.8%) | R superior temporal gyrus (22) | 43 | -29 | -2 | 296 | 9.7 | R precentral gyrus (4) | 31 | -15 | 46 | 6192 | 4.7 | |||||
| R rolandic operculum (2.9%) | L fusiform gyrus (20) | -27 | -1 | -30 | 184 | 10.8 | R superior frontal gyrus (25.5%) | ||||||||||
| R cerebellum (VII) | 35 | -65 | -44 | 7064 | 13.8 | L inferior temporal gyrus (21) | -37 | 11 | -32 | 112 | 8.7 | R precentral gyrus (18.3%) | |||||
| L middle temporal gyrus, angular gyrus (39) | -41 | -65 | 24 | 3144 | 13.8 | L medial temporal pole (38) | -47 | 7 | -20 | 104 | 8.9 | R SMA (10.9%) | |||||
| L anterior cingulate cortex (24) | -11 | 27 | 32 | 2040 | 10.7 | L lingual gyrus (17/18) | -21 | -67 | -2 | 96 | 8.2 | R middle cingulate cortex (4.9%) | |||||
| L cerebellum (VIII) | -33 | -47 | -38 | 1928 | 10.0 | R cerebellum (X) | 25 | -33 | -34 | 80 | 8.0 | R middle frontal gyrus (3.3%) | |||||
| L superior occipital gyrus (19) | -25 | -71 | 34 | 1320 | 9.7 | R middle frontal gyrus (9) | 31 | 27 | 36 | 1328 | 4.2 | ||||||
| L superior temporal gyrus (22) | -61 | -33 | 10 | 712 | 11.6 | ||||||||||||
| R lingual gyrus (17/18) | 15 | -93 | -10 | 450 | 10.4 | TD > ASD | |||||||||||
| L inferior occipital gyrus (18) | -21 | -89 | -10 | 384 | 8.6 | No significant effects | |||||||||||
| L inferior parietal lobule (40) | -45 | -43 | 40 | 384 | 9.5 | ||||||||||||
| L superior medial gyrus (9) | -3 | 43 | 20 | 128 | 8.2 | ||||||||||||