. Author manuscript; available in PMC: 2014 Nov 1.

Published in final edited form as: Trends Neurosci. 2013 Aug 20;36(11):10.1016/j.tins.2013.07.002. doi: 10.1016/j.tins.2013.07.002

Table 2. Microarray studies on neurodegenerative diseases reveal a reduction in NMNAT2 transcript in affected regions of the brain.

Microarray data was mined using NextBio from publicly available array results.

Disease	Tissue / Cell Type	Fold changes	P-value	Reference
Alzheimer’s Disease	Pyramidal cell of hippocampus	−3.81	0.000031	[92, 93]
Alzheimer’s Disease	Pyramidal cell of middle temporal gyrus	−9.25	0.000058	[92, 93]

FTLDU	Hippocampus	−6.22	0.0026	[94]

Parkinson’s Disease	Medial substantia nigra	−2.36	0.0009	[95, 96]
Parkinson’s Disease	Lateral substantia nigra	−2.53	0.0038	[95, 96]

Huntington’s Disease	Caudate nucleus	−3.08	0.0031	[97]
Huntington’s Disease	Motor cortex BA4	−1.36	0.0179	[97]