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. 2014 Jan;21(1):102–111. doi: 10.1177/1933719113492211

Figure 2.

Figure 2.

Effects of E2β, 2OHE2, 4OHE2, 2ME2, and 4ME2 on (A) IOSE-385 and (B) OVCAR-3 proliferation. Cells seeded (1000 and 5000 cells/well for IOSE-385 and OVCAR-3, respectively) were treated with E2β and its metabolites for 6 days. Data are expressed as mean ± SEM fold of the vehicle control (n = 4). *Differs from the vehicle control (P ≤ .05). E2β indicates estradiol 17β; SEM, standard error of the mean; 2ME2, 2-methoxyestradiol; 4ME2, 4-methoxyestradiol; 2OHE2, 2-hydroxyestradiol; 4OHE2, 4-hydroxyestradiol.