Table 1.
IOSE-385 | OVCAR-3 | SKOV-3 | OVCA-432 | |
---|---|---|---|---|
CYP1A1 | 0.36 ± 0.19b | 0.04 ± 0.02b | 0.30 ± 0.30 | ND |
CYP1B1 | 1.10 ± 0.19b | 1.21 ± 0.09b | 0.75 ± 0.19 | 1.07 ± 0.22 |
COMT | 1.17 ± 0.57c | 0.18 ± 0.06 | 0.56 ± 0.04 | 0.07 ± 0.02 |
ERα | 0.35 ± 0.14 | 0.78 ± 0.08 | 0.38 ± 0.14 | 1.96 ± 0.16c |
ERβ | 0.19 ± 0.07 | 1.13 ± 0.35 | 0.16 ± 0.10 | 1.63 ± 0.12c |
Abbreviations: COMT, catechol-O-methyltransferase; CYP1A1, cytochrome P450, family 1, subfamily A; CYP1B1, cytochrome P450, family 1, subfamily B; ERα, estrogen receptor α; ND, not detectable; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; SEM, standard error of the mean.
a Data normalized to GAPDH are expressed as mean ± SEM (P ≤ .05, n = 3).
b Differs from each other within each individual cell line.
c Differs from other cell lines.