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. 2013 Dec 3;8(12):e82396. doi: 10.1371/journal.pone.0082396

Figure 8. Summary of the suggested mechanisms underlying myelopoietic action of orlistat.

Figure 8

Myelopoietic action of orlistat in tumor bearing hosts leads to augmented differentiation of Mϕ with M1 phenotype. Modulated expression of cytokines, cell survival and differentiation regulatory molecules play a central role.