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. 2013 Dec 9;8(12):e81329. doi: 10.1371/journal.pone.0081329

Table 4. Stratification analysis of male gender on association between CXCL10 promoter polymorphisms (−135G>A and −1447A>G) and cerebral malaria.

CXCL10 Non-CM CM OR (95% CI) p value
polymorphism (n = 35) (n = 28)
−135G>A
G/G 21 (60.0%) 25 (89.3%) 1.00 (Ref.)
G/A 14 (40.0%) 3 (10.7%) 0.19 (0.05–0.78) 0.021
A/A - -
G allele 0.8 0.946
A allele 0.2 0.054
−1447A>G
A/A 19 (54.3%) 8 (28.6%) 1.00 (Ref.)
A/G 14 (40.0%) 20 (71.4%) 5.47 (1.34–22.29) 0.018
G/G 2 (5.7%) -
A allele 0.743 0.643
G allele 0.257 0.357

CM  =  cerebral malaria; OR  =  odds ratio; CI  =  confidence interval