Table 4. Stratification analysis of male gender on association between CXCL10 promoter polymorphisms (−135G>A and −1447A>G) and cerebral malaria.
CXCL10 | Non-CM | CM | OR (95% CI) | p value |
polymorphism | (n = 35) | (n = 28) | ||
−135G>A | ||||
G/G | 21 (60.0%) | 25 (89.3%) | 1.00 (Ref.) | |
G/A | 14 (40.0%) | 3 (10.7%) | 0.19 (0.05–0.78) | 0.021 |
A/A | - | - | ||
G allele | 0.8 | 0.946 | ||
A allele | 0.2 | 0.054 | ||
−1447A>G | ||||
A/A | 19 (54.3%) | 8 (28.6%) | 1.00 (Ref.) | |
A/G | 14 (40.0%) | 20 (71.4%) | 5.47 (1.34–22.29) | 0.018 |
G/G | 2 (5.7%) | - | ||
A allele | 0.743 | 0.643 | ||
G allele | 0.257 | 0.357 |
CM = cerebral malaria; OR = odds ratio; CI = confidence interval