Table 6. Stratification analysis of combined genotype frequencies of CXCL10 polymorphisms in patients with cerebral malaria and non-cerebral malaria.
Gender | Combined genotype | Non-CM | CM | OR (95% CI) | p value | |
−135G>A | −1447A>G | |||||
Male Only | n = 35 | n = 28 | ||||
G/G | A/A | 19 (54.3%) | 8 (28.6%) | 1.00 (Ref.) | ||
G/G | A/G | 2 (5.7%) | 17 (60.7%) | 20.38 (3.06–86.84) | <0.0001 | |
G/A | A/G | 12 (34.3%) | 3 (10.7%) | 0.79 (0.17–3.78) | 0.77 | |
G/A | G/G | 2 (5.7%) | - | |||
Female Only | n = 34 | n = 38 | ||||
G/G | A/A | 18 (52.9%) | 17 (44.7%) | 1.00 (Ref.) | ||
G/G | A/G | - | - | - | ||
G/A | A/G | 16 (47.1%) | 21 (55.3%) | 1.48 (0.58–3.77) | 0.415 | |
G/A | G/G | - | - |
CM = cerebral malaria; OR = odds ratio; CI = confidence interval