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. 2013 Aug 9;23(1):1–11. doi: 10.1093/hmg/ddt387

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Figure 5. — Increased activation of ERK2 in hearts of 20-week-old Lmna^H222P/H222P mice lacking Erk1. (A) Representative immunoblots using antibodies against phosphorylated ERK2, total ERK2 and GAPDH to probe proteins extracted from hearts of 16-week-old and 20-week-old Lmna^+/+/Erk1^−/− and Lmna^H222P/H222P/Erk1^−/− mice. (B) Bar graphs showing quantification of pERK2/ERK2 in hearts of 16-week-old and 20-week-old Lmna^+/+/Erk1^−/− and Lmna^H222P/H222P/Erk1^−/− mice. Values are means ± standard errors (n = 3). ***P < 0.0005; n.s., not significant.