Table 2.
Characteristic | n | Median (25th, 75th) of baseline resting heart rate | Median (25th, 75th) of baseline chronotropic index |
---|---|---|---|
Sex | |||
Male | 720 | 70 (61–78) | 54 (41–69) |
Female | 398 | 71 (63–79) | 59 (45–74) |
Race | |||
Black or African American | 437 | 72 (63–79) | 55 (42–71) |
White | 598 | 70 (62–78) | 56 (43–70) |
Other | 83 | 68 (61–77) | 56 (38–72) |
Region | |||
USA | 971 | 71 (63–79) | 56 (42–72) |
Canada | 94 | 68 (62–77) | 48 (39–61) |
France | 53 | 70 (59–80) | 55 (47–66) |
Baseline NYHA class | |||
II | 771 | 70 (61–78) | 59 (47–73) |
III/IV | 347 | 72 (64–80) | 48 (34–63) |
CCS angina class | |||
No angina | 941 | 70 (62–79) | 56 (43–71) |
I | 92 | 71 (62–77) | 60 (47–73) |
II–IV | 85 | 71 (62–77) | 46 (36–60) |
Aetiology | |||
Ischaemic | 512 | 68 (61–76) | 53 (39–66) |
Non-ischaemic | 606 | 72 (64–81) | 57 (46–73) |
Diabetes | |||
No | 749 | 69 (61–78) | 58 (45–73) |
Yes | 369 | 72 (64–80) | 51 (37–65) |
Mitral regurgitation | |||
Non-severe/nonea | 918 | 70 (62–78) | 56 (44–71) |
Severeb | 116 | 72 (61–80) | 54 (37–72) |
Ventricular conduction prior to CPX | |||
Normal | 661 | 71 (62–79) | 56 (42–71) |
LBBB | 233 | 69 (62–77) | 58 (48–72) |
RBBB | 44 | 73 (64–79) | 57 (36–70) |
IVCD | 152 | 70 (63–78) | 53 (39–68) |
ACE inhibitor | |||
No | 254 | 71 (63–78) | 56 (42–70) |
Yes | 864 | 70 (62–79) | 56 (42–71) |
Angiotensin II receptor blocker | |||
No | 863 | 70 (62–79) | 55 (41–71) |
Yes | 255 | 71 (63–78) | 57 (44–71) |
Aldosterone antagonist | |||
No | 635 | 70 (62–78) | 56 (42–71) |
Yes | 483 | 71 (63–79) | 55 (42–71) |
Digoxin | |||
No | 670 | 70 (62–78) | 57 (43–72) |
Yes | 448 | 70 (63–79) | 53 (40–68) |
Loop diuretic | |||
No | 278 | 69 (61–77) | 60 (47–75) |
Yes | 840 | 71 (63–79) | 54 (41–69) |
Non-loop diuretic | |||
No | 1013 | 70 (62–78) | 56 (43–71) |
Yes | 105 | 72 (62–79) | 53 (39–70) |
CCS, Canadian Cardiovascular Society; LBBB, left bundle branch block; RBBB, right bundle branch block; IVCD, intraventricular conduction delay.
aA combination of these original categories: none, trivial, mild, mild to moderate, and moderate.
bA combination of the original categories: severe and moderate to severe.