Table 7.

Relative concentration of NT-proBNP in patients with acute exacerbation of COPD

	Relative NT-proBNP	P-value
Age (per 5 years)	1.4 (1.2–1.6)	<0.0001
Female	1.4 (0.84–2.2)	0.221a
CRP quartile		0.059b (for trend)
1. (<9 mg/L)	1
2. (9–29 mg/L)	1.1 (0.75–1.6)	0.635
3. (29–73 mg/L)	1.3 (0.86–1.9)	0.224
4. (≥73 mg/L)	1.7 (1.1–2.7)	0.014
Pulmonary congestion by routine assessment	1.6 (0.96–2.6)	0.069
Pulmonary congestion by standardized assessment	1.8 (1.2–2.6)	0.003

Notes: The results were analyzed in a linear mixed model with 218 observations from 99 patients.

^aSex was kept in the model by convention

^bCRP was kept in the model in spite of P>0.05 as its removal resulted in poorer model fit.

Abbreviations: COPD, chronic obstructive pulmonary disease; CRP, C-reactive protein; NT-proBNP, N-terminal prohormone of brain natriuretic peptide.