Table 4.
DE (95% CI) × 10 −5 | IE (95% CI) × 10 −5 | TE (95% CI) × 10 −5 | IE/TE (95% CI) | |
---|---|---|---|---|
ER-positive breast cancers (n = 401) | ||||
BMI (5-unit increase) | 16.9 (−7.4 to 41.1) | 16.1 (7.5–25.2) | 33.0 (10.3–55.5) | 0.488 (0.188–1.611) |
Alcohol consumption | ||||
Abstainers → <7 drinks/wk | 58.0 (−0.3 to 116.2) | −0.3 (−6.3 to 5.7) | 57.8 (−0.9 to 116.3) | −0.005 (−0.255 to 0.191) |
Abstainers → 7+ drinks/wk | 183.0 (76.0–289.6) | 5.8 (−2.9 to 16.7) | 188.9 (81.4–296.0) | 0.031 (−0.017 to 0.110) |
ER-negative breast cancers (n = 163) | ||||
BMI (5-unit increase) | 15.2 (0.9–29.6) | −3.0 (−7.9 to 1.7) | 12.1 (−0.1 to 24.4) | −0.248 (−1.430 to 0.468) |
Alcohol consumption | ||||
Abstainers → <7 drinks/wk | −11.9 (−41.7 to 17.8) | 0.1 (−1.6 to 1.8) | −11.9 (−41.6 to 17.9) | −0.008 (−0.394 to 0.398) |
Abstainers → 7+ drinks/wk | −31.0 (−72.0 to 9.8) | −1.1 (−4.9 to 1.1) | −32.1 (−73.0 to 8.7) | 0.034 (−0.199 to 0.367) |
NOTE: Adjusted for age, ethnicity, educational level, marital status, physical activity, smoking, age at menarche, age at menopause, parity, age at first child's birth, and first-degree relative with breast cancer.