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. 2013 Dec 10;8(12):e82968. doi: 10.1371/journal.pone.0082968

Figure 3. Klotho decreased the expression of GRP78 in mouse heart.

Figure 3

(A) Representative images of immunohistochemical staining for GRP78, in CON, ISO and ISO+KL groups for 2, 5 and 9 days. Scale bar=50 um, 400×.(B) Quantitative plot of average expression of GRP78. The expression level of GRP78 in the ISO+KL group was significantly lower than in the ISO group at day 9. Data are mean±SEM, n=3-4. * P<0.05 between two compared groups; NS, no significance.