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. 2013 Dec 10;8(12):e82997. doi: 10.1371/journal.pone.0082997

Figure 4. Transplantation of AT2R Stimulated BMMNCs Improved Global Heart Function and Reduced Infarct Size.

Figure 4

(A) Representative M-mode images showing cardiac function in each group. (B) Ejection Fraction; (C) Fraction Shortening; (D) LVIDd; and (E) LVIDs. Sham n=5; DMEM group n=8; BMMNCs group n=9; BMMNCs + AngII + Valsartan group n=10; BMMNCs +CGP42112A group n=10; and BMMNCs + AngII + Valsartan + PD123319 group n=9. *P <0.05 versus DMEM group and BMMNCs group, #P < 0.05 versus BMMNCs + AngII + Valsartan +PD123319 group. (F) Intramyocardial transplantation of AT2R stimulated BMMNCs reduced infarct size. DMEM group n=4; BMMNCs group n=5; BMMNCs+AngII+Valsartan group n=6; BMMNCs+CGP42112A group n=5; and BMMNCs+AngII+Valsartan+PD123319 group n=4. *P < 0.05 versus DMEM group and BMMNCs group, # P < 0.05 versus BMMNCs+AngII+Valsartan+PD123319 group.