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. Author manuscript; available in PMC: 2014 Dec 3.
Published in final edited form as: Cell Metab. 2013 Sep 12;18(6):10.1016/j.cmet.2013.08.010. doi: 10.1016/j.cmet.2013.08.010

Figure 1. Types of diabetes and metabolic syndromes.

Figure 1

The various types of diabetes and metabolic syndromes that can be modeled using induced pluripotent stem cells (iPSCs) include monogenic forms of diabetes, Type 1 diabetes (T1D) and Type 2 diabetes (T2D). T1D occurs as a result of immune attack by immune cells such as macrophages and T cells whereas T2D occurs as a result of insulin resistance in the pancreas, muscle, fat and liver. Square represents male subjects whereas circle represents female subjects. Filled symbols denote subjects with diabetes.