Table 2.

Summary of Serum Half-Life Data in humanized FcRn mice

Antibody	Route	Dose	Half-Life (h)	Mouse Strain	Reference
Adalimumab	IV	10 mg/kg	86	Tg276 hemi	[18]
Basiliximab	IV	10 mg/kg	120	Tg276 hemi	[18]
Bevacizumab	IV	10 mg/kg	76	Tg276 hemi	[18]
Bevacizumab	IV	2 mg/kg	67–70	Tg276 hemi	[27]
Cetuximab	IV	10 mg/kg	66	Tg276 hemi	[18]
Cetuximab	IV	2 mg/kg	70	Tg276 hemi	[27]
Trastuzumab	IV	10 mg/kg	81	Tg276 hemi	[18]
Trastuzumab	IV	10 mg/kg	56	Tg276 hemi	[24]
Trastuzumab	IP	5 mg/kg	41	Tg276 hemi	[23]
Trastuzumab	IP	5 mg/kg	139	Tg276 homo	[23]
Trastuzumab	IP	5 mg/kg	155	Tg32 hemi	[23]
Trastuzumab	IP	5 mg/kg	242	C57BL6/J	[23]