Table 3.
Baseline characteristics of patients with an identifiable culprit artery
| Characteristic | No Collaterals (n=63) | Collaterals (n=52) | P value |
|---|---|---|---|
| Age (years) mean +/− SD | 60 (+/− 12) | 62 (+/− 11) | 0.542 |
| Men | 46 (73%) | 43 (83%) | 0.217 |
| Hypertension * | 52 (83%) | 39 (75%) | 0.322 |
| Hyperlipidemia † | 52 (83%) | 44 (85%) | 0.765 |
| Diabetes mellitus | 21 (33%) | 16 (31%) | 0.770 |
| Current smoker | 26 (41%) | 15 (29%) | 0.166 |
| Former smoker | 18 (29%) | 18 (35%) | 0.487 |
| Prior angina | 32 (51%) | 21 (40%) | 0.265 |
| Prior MI | 18 (29%) | 17 (33%) | 0.633 |
| Prior PCI | 18 (29%) | 16 (31%) | 0.797 |
| Prior CABG | 8 (13%) | 11 (21%) | 0.224 |
| History of CHF | 6 (10%) | 0 | 0.031 |
| History of arrhythmia | 2 (3%) | 5 (10%) | 0.150 |
| Prior stroke | 2 (3%) | 4 (8%) | 0.407 |
| Family history of CAD | 35 (56%) | 24 (46%) | 0.273 |
| Peripheral arterial disease | 7 (11%) | 11 (21%) | 0.140 |
| Left ventricular ejection fraction ‡ | 0.644 | ||
| Normal | 34 (54%) | 23 (44%) | |
| Mild-moderately depressed | 8 (13%) | 13 (25%) | |
| Severely depressed | 1 (2%) | 0 | |
| Labs | |||
| Total cholesterol (mg/dL) | 173 [138–204] | 184 [150–227] | 0.438 |
| LDL (mg/dL) | 110 [80–136] | 117 [90–133] | 0.416 |
| HDL (mg/dL) | 31 [24–41] | 33 [28–43] | 0.390 |
| Triglycerides (mg/dL) | 152 [76–199] | 163 [86–215] | 0.766 |
| Troponin I (ng/mL) | 2.30 [0.38–16.53] | 2.14 [0.39–9.87] | 0.527 |
| Medications | |||
| Aspirin | 59 (94%) | 48 (92%) | 1.000 |
| Clopidogrel | 29 (47%) | 24 (46%) | 0.947 |
| Statin | 55 (89%) | 47 (90%) | 0.772 |
| Oral Hypoglycemic | 4 (6%) | 4 (8%) | 1.000 |
| Insulin | 10 (16%) | 16 (31%) | 0.057 |
| Beta Blocker | 51 (82%) | 41 (79%) | 0.646 |
| Calcium Channel Blocker | 4 (6%) | 4 (8%) | 1.000 |
| ACE-Inhibitor | 37 (60%) | 19 (37%) | 0.014 |
Data are expressed as mean ± standard deviation (SD), median [25–75% interquartile range (IQR)], or as number (percentage), ACE= angiotensin converting-enzyme, CABG= coronary artery bypass graft surgery, CAD= coronary artery disease, CHF= congestive heart failure, HDL= high density lipoprotein, LDL = low density lipoprotein, MI= myocardial infarction, PCI= percutaneous coronary intervention.
patients treated with antihypertensive medication, and untreated patients with known systolic blood pressure ≥140mmHg or diastolic blood pressure ≥90mmHg
patients with total cholesterol level >200mg/dl, or current use of lipid-lowering drugs
as determined by left ventriculography or transthoracic echocardiography, normal left ventricular systolic function was defined as an ejection fraction of ≥55%, mild to moderately depressed left ventricular function was defined as an ejection fraction of 40–54%, and severely depressed left ventricular systolic function was defined as an ejection fraction of <40%.