Table 5.
Long-term clinical outcomes according to the presence or absence of angiographic collaterals
| Entire cohort N=269 | Collaterals (N=96) | No Collaterals (N=173) | Unadjusted HR (95% CI) | Unadjusted P value | Adjusted HR* (95% CI) | Adjusted P value |
|---|---|---|---|---|---|---|
| Death, n (%) | 9 (9.9) | 4 (2.4) | 4.17 (1.28–13.53) | 0.018 | 3.52 (0.88–14.00) | 0.074 |
| Recurrent MI, n (%) | 4 (4.6) | 2 (1.4) | 3.72 (0.68–20.34) | 0.129 | 2.60 (0.30–22.47) | 0.386 |
| Recurrent angina, n (%) | 19 (21.0) | 22 (13.6) | 1.67 (0.90–3.08) | 0.102 | 1.31 (0.64–2.69) | 0.466 |
| Stroke, n (%) | 0 | 2 (1.3) | --- | --- | --- | --- |
| Arrhythmia, n (%) | 4 (4.4) | 6 (3.2) | 1.26 (0.36–4.48) | 0.717 | 3.39 (0.48–24.05) | 0.223 |
| CHF, n (%) | 6 (6.7) | 7 (4.4) | 1.59 (0.53–4.73) | 0.405 | 8.05 (1.36–47.58) | 0.021 |
| PCI, n (%) | 6 (6.7) | 5 (3.2) | 2.22 (0.68–7.26) | 0.189 | 1.62 (0.41–6.42) | 0.495 |
| CABG, n (%) | 18 (19.0) | 9 (5.3) | 3.87 (1.74–8.61) | 0.001 | 1.43 (0.62–3.31) | 0.404 |
| Combined endpoint,† n (%) | 35 (37.4) | 29 (17.7) | 2.56 (1.56–4.19) | <0.001 | 1.95 (1.08–3.52) | 0.027 |
| Known culprit artery N=115 | Collaterals (N=52) | No Collaterals (N=63) | Unadjusted HR (95% CI) | Unadjusted P value | Adjusted HR** (95% CI) | Adjusted P value |
|---|---|---|---|---|---|---|
| Death, n (%) | 3 (6.0) | 2 (3.3) | 1.90 (0.32–11.35) | 0.484 | 10.59 (0.61–185.05) | 0.106 |
| Recurrent MI, n (%) | 1 (1.9) | 1 (1.8) | 1.28 (0.08–20.52) | 0.860 | --- | --- |
| Recurrent angina, n (%) | 8 (15.8) | 8 (13.6) | 1.31 (0.49–3.50) | 0.586 | 2.50 (0.68–9.13) | 0.165 |
| Stroke, n (%) | 0 | 0 | --- | --- | --- | --- |
| Arrhythmia, n (%) | 2 (3.9) | 1 (1.8) | 2.55 (0.23–28.20) | 0.444 | --- | --- |
| CHF, n (%) | 2 (4.3) | 2 (3.4) | 1.29 (0.18–9.18) | 0.798 | 1.66 (0.11–24.05) | 0.712 |
| PCI, n (%) | 3 (5.8) | 3 (5.1) | 1.27 (0.26–6.28) | 0.772 | 3.19 (0.24–41.77) | 0.377 |
| CABG, n (%) | 6 (11.5) | 3 (4.9) | 2.59 (0.65–10.36) | 0.179 | 13.46 (1.23–147.62) | 0.033 |
| Combined endpoint,† n (%) | 13 (25.3) | 10 (16.5) | 1.79 (0.78–4.08) | 0.167 | 3.71 (1.31–10.57) | 0.014 |
CABG=coronary artery bypass surgery; CHF=congestive heart failure; CI=confidence interval; HR=hazard ratio; MI=myocardial infarction; PCI=percutaneous coronary intervention.
*
Adjusted for age (>=65 vs <65), gender, history of diabetes, history of CHF, history of MI, extent of coronary artery disease, and peak troponin;
**
Adjusted for age (>=65 vs <65), gender, history of diabetes, history of CHF, history of MI, extent of coronary artery disease, peak troponin, and initial TIMI flow in culprit artery, and stent.
†
combined endpoint of death, recurrent MI, PCI, CABG stroke, and PCI.