Figure 22.

Sequence alignment and structure of LRAT-like acyltransferase enzymes. A protein sequence alignment of all LRAT-like proteins encoded in the human genome is displayed on the left, showing conserved His and Cys residues (orange) that constitute the catalytic triad of this enzyme family. Hydrophobic C-terminal membrane-anchoring sequences are colored green. The crystallographic structure of human HRASLS3 is shown on the right with the carbon atoms of residues comprising the catalytic triad colored orange.